• Iñigo-Marco I., Valencia M., Larrea L., Bugallo R. , Martínez-Goikoetxea M., Zuriguel I. and Arrasate M. (2017) E46K alpha-synuclein pathological mutation causes cell-autonomous dependent toxicity without altering protein turnover and aggregation. Proc. Natl. Acad. Sci. USA, 114(39): E8274-E8283.

  • Tsvetkov AS., Arrasate M., Barmada S., Ando M.D., Sharma P., Shaby B.A., and Finkbeiner S. (2013) Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration. Nature Chemical Biology, Sep;9(9):586-92.

  • Miller* J., Arrasate* M., Brooks E., Peters-Libeu C., Legleiter J., Hatters D., Curtis J., Cheung K., Krishnan P., Mitra S., Widjaja K., Shaby B.A., Lotz G.P.Newhouse Y., Mitcell E., Osmand A., Gray M., Thulasiramin V., Saudou F, Muchowski P.J., Segal M., Yang W.X., Masliah E., Thompson L.M., Muchowski P.J., Weisgraber K. H., and Finkbeiner S. Identifying polyglutamine protein species in situ that best predict neurodegeneration. (2011) Nature Chemical Biology, 7(12):925-34 (*equal contribution).

  • Tsvetkov, A.S., Miller, J., Arrasate, M., Wong J.S., Pleiss, M.A., Finkbeiner, S. (2010). A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington´s disease model. Proc. Natl. Acad. Sci. USA, 107 (39) 16982-16987.

  • Arrasate M. and Finkbeiner S. (2005). Automated microscope system for determining factors that predict neuronal fate. Proc. Natl. Acad. Sci. USA, 102 (10) 3840-5.

  • Arrasate M., Mitra S., Schweitzer E., Segal M. and Finkbeiner S. (2004). Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature, 431 (7010): 805-810.


Dra. Montserrat Arrasate

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