Pipeline. Universidad de Navarra

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Fecha de actualización: julio de 2019

Discovery

Click for more info Project Teaser	Indication	Target
CM-352	Surgical Bleeding Research Group	MMP10 & MMP3
CM-272	Cancer Research Group	DNMT & G9a
CM-414	Alzheimer’s Disease Research Group	PDE5 & HDACs
CM-1315	Onco-immunology Research Group	Disruption of FOXP3 dimerization
Apo-Insulin	Diabetes Research Group	Insulin Receptor
Sushi-IL15- Apo	Onco-immunology Research Group	Receptor IL-15
Apo- FGF19	Liver regeneration Research Group	FGF19 receptor

Target ID	In vitro Assays	Hit ID	In vivo PoC / Lead id	ADMET / PK Optimización	Preclinical	Clinical

IP

Small molecules Macrocycles Aptamers Gene Theraphy Biologics Cell Therapy

Early Discovery

Click for more info Project Teaser	Indication	Target
CM-166	Heart Failure fibrosis Research Group	Novel Target (undisclosed)
Viro Therapy	Onco-immunology Research Group	Inmune response
Eliratra	Onco-immunology Research Group	Immune response
CM-1351	Onco-immunologyResearch Group	Disruption Foxp3/ NFAT interaction
CM-3132	Dravet Syndrome Research Group	SCN1A

Target ID	In vitro Assays	Hit ID	In vivo PoC / Lead id	ADMET / PK Optimización

Partners	IP
Undisclosed	in-process


Undisclosed	in-process
	in-process

Small molecules Macrocycles Aptamers Gene Theraphy Biologics Cell Therapy

Licensed Products in PreClinical & Clinical Phases

Click for more info Project Teaser	Indication
CardioPatch	Heart Failure Research Group
EDA vaccine	Cervical Cancer Research Group
CM-1349	Acute intermittent porphyria Research Group
a5-IFN	Manufacturing
rh-CT 1 *	Acute kidney injure
AAV-PBGD *	Acute intermittent Porphyria
CM-144 *	Scleroderma
AAV-GBA	GT for CNS

R&D	Preclinical

Phase I	Phase II	Phase III

Licensed	IP

* Terminated

Small molecules Macrocycles Aptamers Gene Therapy Biologics Cell Therapy

Diagnostics

Click for more info Project Teaser	Indication
C4 activation fragment	Lung Cancer Research Group
BM Panel	Heart Failure Research Group
ADC Pronostic Index	Lung adenocarcinoma Research Group
SCC Pronostic Index	Lung squamous cells carcinoma Research Group

Biomarker identification	Analytical Validation

Retrospective Clinical Validation	Protrospective Clinical Validation	Regulation Process	Clinical Utility

Partners	Licensed	IP

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