Publicaciones

Neurociencia Fundamental

  • Fiuza M, González-González I, Pérez-Otaño I. GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling. Proc Natl Acad Sci U S A (2013) 110:20807-12. IF = 9.737. MULTIDISCIPLINARY SCIENCES 4/56, 1er Decil.
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  • Marco S, Giralt A, Petrovic MM, Pouladi MA, Martínez-Turrillas R, Martínez-Hernández J, Kaltenbach LS, Torres-Peraza J, Watanabe M, Luján R, Nakanishi N, Lipton SA, Lo DC, Hayden MR, Alberch J, Wesseling JF, Pérez-Otaño I. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine (2013) 8:1030-8. IF = 24.302. MEDICINE, RESEARCH & EXPERIMENTAL 1/121, 1er Decil.
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  • Gabriel T, García-Pérez E, Mahfooz K, Goñi J, Martínez-Turrillas R, Pérez-Otaño I, Lo DC, Wesseling JF. A new kinetic framework for synaptic vesicle trafficking tested in synapsin knock-outs. J Neurosci. (2011), 31:11563-77. IF= 7.115. NEUROSCIENCES 19/244, 1er Decil.
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  • Roberts AC, Díez-García J, Rodriguiz RM, López IP, Luján R, Martínez-Turrillas R, Picó E, Henson MA, Bernar- do DR, Jarrett TM, Clendeninn DJ, López-Mascaraque L, Feng G, Lo DC, Wesseling JF, Wetsel WC, Philpot BD, Pérez-Otaño I. Developmental down-regulation of NR3A-containing NMDA receptors is required for synapse ma- turation and memory consolidation. Neuron. (2009) 63; 342-356 IF= 13.260. NEUROSCIENCES 6/231, 1er Decil.

  • Miller J*, Arrasate M*, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, Osmand A, Gray M, Thulasiramin V, Saudou F, Segal M, Yang XW, Masliah E, Thompson LM, Muchowski PJ, Weisgraber KH, Finkbeiner S. Identifying polygluta- mine protein species in situ that best predict neurodegeneration. Nature Chemical Biology (2011), 7:925-34 (*equal contribution). IF= 14.690. BIOCHEMISTRY & MOLECULAR BIOLOGY 4/290, 1er Decil.
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  • Lopez-Azcarate, J; Nicolas, MJ; Cordon, I; Alegre, M; Valencia, M*; Artieda, J* (*equal contribution). Delta-mediated cross-frequency coupling organizes oscillatory activity across the rat cortico-basal ganglia ne- twork. FRONTIERS IN NEURAL CIRCUITS.2013; IF: 3,333. Lugar: 97/251 (2º Cuartil).
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  • Alegre, M; Lopez-Azcarate, J; Obeso, I; Wilkinson, L; Rodriguez-Oroz, MC; Valencia, M; Garcia-Garcia, D; Guridi, J; Artieda, J; Jahanshahi, M; Obeso, JA. The subthalamic nucleus is involved in successful inhibition in the stop-signal task: A local field potential study in Parkinson's disease. EXPERIMENTAL NEUROLOGY.2013; IF:4,645. Lugar: 48/251 (1er Cuartil).
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  • Rodriguez-Oroz, MC; Lopez-Azcarate, J; Garcia-Garcia, D; Alegre, M; Toledo, J; Valencia, M; Guridi, J; Artieda, J; Obeso, JA. Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinson's disease. BRAIN.2011; IF:9,457. Lugar: 12/244 (1er Decil).
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  • Unzu, C; Sampedro, A; Mauleon, I; Alegre, M; Beattie, SG; de Salamanca, RE; Snapper, J; Twisk, J; Petry, H; Gonzalez-Aseguinolaza, G; Artieda, J; Rodriguez-Pena, MS; Prieto, J; Fontanellas, A. Sustained Enzymatic Correction by rAAV-Mediated Liver Gene Therapy Protects Against Induced Motor Neuropathy in Acute Por- phyria Mice. MOLECULAR THERAPY.2011; IF:6,873. Lugar: 10/110 (1er Decil).
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  • Lopez-Azcarate, J; Tainta, M; Rodriguez-Oroz, MC; Valencia, M; Gonzalez, R; Guridi, J; Iriarte, J; Obeso, JA; Artieda, J; Alegre, M. Coupling between beta and high-frequency activity in the human subthalamic nucleus may be a pathophysiological mechanism in Parkinson's disease. JOURNAL OF NEUROSCIENCE.2010; IF:7,271. Lugar: 17 (1er Decil).
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Neurobiología de Enfermedades Neurodegenerativas

  • Ricobaraza A, Cuadrado-Tejedor M, Pérez-Mediavilla A, Frechilla D, Del Río J, García-Osta A. Phenyl- butyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer´s disease mouse model. Neuropsychopharmacology 34: 1721-32 (2009). IF: 6.993. NEUROSCIENCES 18/231. 1er Decil.
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  • Ricobaraza A, Cuadrado-Tejedor M, Marco S, Pérez-Otaño I*, García-Osta A* Phenylbutyrate recues den- dritic spine loss associated with memory deficits in a Mouse model of Alzheimer´s disease. Hippocampus 22:1040-50 (2012). IF: 5.492. NEUROSCIENCES 36/231. 1er Cuartil.
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  • Cuadrado-Tejedor M, Hervias I, Ricobaraza A, Puerta E, Pérez-Roldán JM, García-Barroso C, Franco R, Aguirre N, García-Osta A. Sildenafil restores cognitive function without affecting -amyloid burden in a mouse model of Alzheimer's disease. Br J Pharmacol. 164:2029-41 (2011). IF: 4.409. PHARMACOLOGY & PHAR- MACY 35/261. 1er Cuartil.
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  • Chen DY, Stern SA, Garcia-Osta A, Saunier-Rebori B, Pollonini G, Bambah-Mukku D, Blitzer RD, Alberini CM. A critical role for IGF-II in memory consolidation and enhancement. Nature, 469: 491-7 (2011). IF: 36.28. MULTIDISCIPLINARY SCIENCES 1/56. 1er Decil.
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  • Gil-Bea F, Akterin S, Persson T, Mateos L, Sandebring A, Avila-Cariño J, Gutierrez-Rodriguez A, Sunds- tröm E, Holmgren A, Winblad B, Cedazo-Minguez A. Thioredoxin-80 is a product of alpha-secretase clea- vage that inhibits amyloid-beta aggregation and is decreased in Alzheimer's disease brain. EMBO Mole- cular Medicine, 4 - 10, 1097 – 1111 (2012). IF: 7.795. MEDICINE, RESEARCH & EXPERIMENTAL 9/121. 1er Decil.
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  • Mundiñano IC, Hernandez M , DiCaudo C, Ordóñez C, Marcilla I, Tuñon MT, Luquin MR. Reduced choliner- gic olfactory centrifugal inputs are in patients with neurodegenerative disorders and MPTP-treated monkeys. Acta Neuropathology (2013) 126:411-25. IF: 9.73, NEUROSCIENCES 11/252. 1er Decil.
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  • Luquin N, Sierra S, Rico AJ, Gómez-Bautista V, Roda E, Conte-Perales L, Franco R, McCormick P, Laban- deira-García JL, Lanciego JL.. Unmasking adenosine 2A receptors (A2ARs) in monkey basal ganglia output neurons using cholera toxin B subunit (CTB). Neurobiology of Disease (2012) 47:347-57. IF: 5.624. NEURO- SCIENCES 34/252. 1ercuartil.
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  • Lanciego JL, Vázquez A. The basal ganglia and thalamus of the long-tailed macaque in stereotaxic coordi- nates: A template atlas based on coronal, sagital and horizontal brain sections. Brain Structure and Function (2012) 217:613-66. IF: 7.837, NEUROSCIENCES 18/252, 1er Decil.
    ABSTRACT CORTESÍA DE PUBMED

  • Conte-Perales L, Rico AJ, Barroso-Chinea P, Gómez-Bautista V, Roda E, Luquin N, Sierra S, Lanciego JL. Pallidothalamic-projecting neurons in Macaca fascicularis co-express GABAergic and glutamatergic markers as seen in control, MPTP-treated and dyskinetic monkeys. Brain Structure and Function (2011) 216:371-86. IF: 5.628, NEUROSCIENCES 33/244. 1er Cuartil.
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  • Navarro G, Aymerich MS, Marcellino D, Cortés A, Casadó V, Mallol J, Canela EI, Agnati L, Woods AS, Fuxe K, Lluís C, Lanciego JL, Ferré S, Franco R. Interactions between calmodulin, adenosine A2A and dopamine D2 receptors. Journal of Biological Chemistry 2009 284:28058-68. IF= 5.33. BIOCHEMISTRY & MOLECU- LAR BIOLOGY, 48/283 1er Cuartil.
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"Tratamos de identificar los factores que dan origen al proceso neurodegenerativo para diseñar nuevas estrategias experimentales que permitan detectar y tratar la enfermedad en fases tempranas", Dra. Isabel Pérez-Otaño, directora del programa.

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Contacto:
Cristina Canciani
Avda. Pío XII, 53
31008 Pamplona
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(+34) 948 194 700 Ext. 2013
canciani@unav.es