Study of the liver's cell and molecular response to acute and chronic damage.

The laboratory's objectives are:

  1. To develop liver-protection strategies aimed at recovering liver function and its regenerative ability and that allow for a reduction in mortality in patients with acute liver failure; to utilize these strategies in organ transplants that are considered marginal (fatty livers, livers in elderly patients and livers of small size); to perform broader partial extirpations and extirpations in organs with a compromised regenerative ability.

  2. To find new therapeutic strategies that enable steatosis and cirrhosis to be treated in order to recover liver function; to reduce the need for liver transplant; and to prevent development of liver cancer.

  3. To identify and characterize effective molecular targets for the treatment of liver cancer.

  4. To characterize new markers for early detection and progression of intermittent acute porphyria as well as new therapeutic strategies based on gene therapy and innovative biotechnology products.



"We have identified proteins that can protect liver tissue in acute lesions and we are developing ways in which these proteins can be turned into drugs," , Dr. Matías Ávila, Program Director.

More information:

Contact

Contact:
Cibeles Pinto
Avda. Pío XII, 55
31.008 Pamplona
Spain

(+34) 948 194 700 Ext. 4012
mcpinto@unav.es