Cell Therapy in Osteoarticular Diseases
Because of the increase in life expectancy in developed societies, diseases of the musculoskeletal system are among the leading causes of disability and chronic pain.
The absence of regeneration and repair mechanisms in joint tissue means that any damage derived from a degenerative process that leads to arthrosis is characterized by complete loss of joint function. Current pharmacological treatments are palliative and do not halt disease progression, so there is a need to develop therapies that halt the progression of joint degeneration and activate tissue repair mechanisms.
Our group is interested in the therapeutic potential of mesenchymal stem cells (MSC) for the treatment of these pathologies. Our ultimate objective is to develop effective therapies for the treatment of osteoarticular diseases and their complications, through the use of:
Cell therapies in combination with biomaterials (mimetic grafts).
Analysis and identification of the molecular mechanisms involved in natural tissue regeneration processes.