Publications

  • Llopiz D, Aranda F, Díaz-Valdés N, Ruiz M, Infante S, Belsúe V, Lasarte JJ, Sarobe P. Vaccine-induced but not tumor-derived Interleukin-10 dictates the efficacy of Interleukin-10 blockade in therapeutic vaccination. Oncoimmunology 2015 (Accepted)

  •  Zabaleta A, D'Avola D, Echeverria I, Llopiz D, Silva L, Villanueva L, Riezu-Boj JI, Larrea E, Pereboev A, Lasarte JJ, Rodriguez-Lago I, Iñarrairaegui M, Sangro B, Prieto J, Sarobe P. Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection. Mol Ther Methods Clin Dev. 2015 Mar 11;2:15006. eCollection 2015.

  • Llopiz D, Huarte E, Ruiz M, Bezunartea J, Belsúe V, Zabaleta A, Lasarte JJ, Prieto J, Borrás-Cuesta F, Sarobe P. Helper cell-independent antitumor activity of potent CD8+ T cell epitope peptide vaccines is dependent upon CD40L. Oncoimmunology. 2013 Dec 1;2(12):e27009.

  • Diaz-Valdes, N., L. Manterola, V. Belsue, J. I. Riezu-Boj, E. Larrea, I. Echeverria, D. Llopiz, J. Lopez-Saga- seta, H. Lerat, J. M. Pawlotsky, J. Prieto, J. J. Lasarte, F. Borras-Cuesta, and P. Sarobe. 2011. Improved den- dritic cell-based immunization against hepatitis C virus using peptide inhibitors of interleukin 10. Hepatology 53:23-31. IF (2011): 11.665; Lugar: 2/73 Gastroenterology and Hepatology; 1er cuartil.
    ABSTRACT CORTESÍA DE PUBMED

  • Echeverria I, Pereboev A, Silva L, Zabaleta A, Riezu-Boj JI, Bes M, Cubero M, Borras-Cuesta F, Lasarte JJ, Esteban JI, Prieto J, Sarobe P.  Enhanced T cell responses against hepatitis C virus by ex vivo targeting of adenoviral particles to dendritic cells. Hepatology. 2011;54(1):28-37.

  • Aranda, F., D. Llopiz, N. Diaz-Valdes, J. I. Riezu-Boj, J. Bezunartea, M. Ruiz, M. Martinez, M. Durantez, C. Mansilla, J. Prieto, J. J. Lasarte, F. Borras-Cuesta, and P. Sarobe. 2011Adjuvant combination and antigen targeting as a strategy to induce polyfunctional and high-avidity T-cell responses against poorly immunogenic tumors. Cancer Res 71:3214-3224. IF (2011): 7.856; Lugar: 12/192 Oncology; 1er cuartil.
    ABSTRACT CORTESÍA DE PUBMED

  • Llopiz D, Dotor J, Casares N, Bezunartea J, Díaz-Valdés N, Ruiz M, Aranda F, Berraondo P, Prieto J, Lasarte JJ, Borrás-Cuesta F, Sarobe P. Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy. Int J Cancer.2009 1;125(11):2614-23. 



""We have shown the different strategies that potentiate the activation the dendritic cells increase the effect of the vaccines. This has given rise to different vaccination protocols, which have been trialed in patients", Dr. Pablo Sarobe, Principal Investigator.

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Contact

Contact:
Cristina López
Avda. Pío XII, 55
31008 Pamplona
Spain

(+34) 948 194 700 Ext. 6021
clopezg@unav.es