Early Stage Therapeutic Products
  Indication
Target
CM-352 Bleeding
Disorders
MMP10 & MMP3

Research Group

CM-1186 Wilson’s
Disease
ATP7B

Research Group

CM-272 Cancer
AML & HCC
DNMT & G9a

Research Group

CM-414 Alzheimer’s Disease PDE5 & HDACs

Research Group

CM-695 Stroke in
Atrial
Fibrillation
HSP70

Research Group

Apo-Insulin Diabetes
patients with
NASH
Insulin
Receptor

Research Group

Sushi-IL15-
Apo
Cancer Receptor IL-15

Research Group

CM-1349 Acute
intermittent porphyria
PBGD

Research Group

CM-1565 Acute
intermittent porphyria
PBGD
Inducible

Research Group

Target ID In vitro
Assays
Hit ID In vivo PoC
/ Lead id
ADMET / PK
Optimización
Preclinical Clinical
 
   
   
   
   
     
     
     
     
Partners
Licensed
IP
Digna
Biotech
  ok
Aligen
Therapeutics
  ok
    ok
    ok
    ok
    ok
Digna
Biotech
  ok
Digna
Biotech
  ok
    ok
 

 

Emerging Projects
  Indication
Target
HC-Ad-IL12 Cancer IL 12 Inducible &
long-term expression

Research Group

CM-1215 Onco- immunology Disruption Fox3 dimerization

Research Group

CM-1129 Onco- immunology Disruption Foxp3/ NFAT interaction

Research Group

CM-825 Heart Failure Fibrosis

Research Group

GPCR-X antagonist Alzheimers's Disease GPCR-X

Research Group

CM-1300 B-cell malignancies plC17

Research Group

GluN3A
Huntington's Disease & Drug abuse New target

Research Group

Target ID In vitro
Assays
Hit ID In vivo PoC
/ Lead id
ADMET / PK
Optimización
Preclinical Clinical
 
     
       
       
         
         
           
Partners
Licensed
IP
     
    On-going
    On-going
    On-going
Servier   On-going
     
     
 

 

Licensed Products in (Pre-) Clinical Phases
  Indication
AAV-PBGD Acute intermit-
ent Porphyria

Research Group

CT-1 Acute kidney
injury

 

EDA vaccine Cervical
Cancer

Research Group

R&D Preclinical
Phase I Phase II Phase III
   
   
     
Partners
Licensed
IP
Digna
Biotech
Uniqure ok
Digna
Biotech
Digna
Biotech
ok
Digna
Biotech
Formune
Vaccines
ok
 

 

Early Stage Diagnostics Products
  Indication
C4d Lung Cancer

Research Group

BM Panel Heart Failure

Research Group

Biomarker
identification
Analytical
Validation
Retrospective Clinical
Validation
Protrospective Clinical
Validation
Regulation
Process
Clinical
Utility
     
     
Partners
Licensed
IP
Digna
Biotech
  ok